Armenian Hamster IgG Isotype Control - Purified In vivo GOLD™ Functional Grade - 1.0 mg I-140-1.0 mg from Leinco Technologies, Inc.

Product Specs
ItemArmenian Hamster IgG Isotype Control - Purified In vivo GOLD™ Functional Grade - 1.0 mg
CompanyLeinco Technologies, Inc.
Price Pricing Info Supplier Page View Company Product Page
Catalog NumberI-140-1.0 mg
Quantity1.0 mg
ApplicationsFC, in vivo
Concentration≥ 5.0 mg/ml
Conjugate/Tag/LabelUnconjugated
FormatThis monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added. Due to inherent biochemical properties of antibodies, certain products may be prone to precipitation over time. Precipitation may be removed by aseptic centrifugation and/or filtration
Purity≥95% monomer by analytical SEC, >95% by SDS Page
IsotypeIgG
ClonePIP
HostArmenian Hamster
Antibody TypeIsotype Control
Validated ApplicationsFlow Cytometry (FCM)

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Leinco Technologies, Inc.

410 Axminister Drive

St. Louis, Missouri 63026

United States

Phone: (636) 230-9477
Orders or Customer Support: (800) 538-1145
Technical Support: (800) 538-1145

Email: leincoglobal@leinco.com

Company Profile

Website: www.leinco.com

(1) Regulating macrophage-MSC interaction to optimize BMP-2-induced osteogenesis in the local microenvironmentBioactive materialsJuly 1, 2023Jiang F, Qi X, Wu X, Lin S, Shi J, Zhang W, Jiang X.intraperitoneally on the day before subcutaneous transplantation. The Armenian hamster IgG isotype (I-140, Leinco Technologies; USA) were used as control. There were six mice in each experimental group. 2.6

(2) Myeloid autophagy genes protect mice against fatal TNF- and LPS-induced cytokine storm syndromesAutophagyApril 3, 2023Ya-Ting Wang, Amy Sansone, Asya Smirnov, Christina L. Stallings, Anthony OrvedahlTNF neutralizing antibody (clone TN3–19.2; Leinco, T258) or isotype control antibody (PIP; Leinco, I-140) at a dose of 250 μg/mouse in PBS 72 h prior to LPS injection. Mice were monitored every 6–12 h for

(3) The IFN-Î³ receptor promotes immune dysregulation and disease in STING gain-of-function miceJCI InsightSeptember 8, 2022W. Alexander Stinson, Cathrine A. Miner, Fang R. Zhao, Annena Jane Lundgren, Subhajit Poddar, Jonathan J. Minerantibody, 20 μg/mL anti-mouse IFN-γ antibodies (Leinco, I-438) or isotype control antibody (Leinco, I-140) were incubated with recombinant murine IFN-γ (10 ng/mL) for 30 minutes at room temperature and then

(4) UVB-Induced Skin Autoinflammation Due to Nlrp1b Mutation and Its Inhibition by Anti-IL-1β AntibodyFrontiers in ImmunologyJune 17, 2022Yuya Murase, Takuya Takeichi, Jun Koseki, Yuki Miyasaka, Yoshinao Muro, Tamio Ohno, Teppei Shimamura, Masashi AkiyamaLeinco Technologies, Inc., Missouri, USA), which is specific for IL-1β, or 2 mg/kg IgG Isotype Control (I-140, Leinco Technologies, Inc., Missouri, USA) before UVB irradiation at Day 0. Results We Successfully

(5) A novel miR1983-TLR7-IFNβ circuit licenses NK cells to kill glioma cells, and is under the control of galectin-1OncoimmunologyJanuary 1, 2021Shah D, Comba A, Faisal SM, Kadiyala P, Baker GJ, Alghamri MS, Doherty R, Zamler D, Nuñez G, Castro MG, et al.purified in vivo GOLD™ functional grade Armenian hamster IgG Isotype Control (Leinco technologies, Cat# I-140-5.0, Clone: PIP). For neutralization of IL-12 in vivo, mice were subjected to intraperitoneal injections

(6) Macrophage β2-Integrins Regulate IL-22 by ILC3s and Protect from Lethal Citrobacter rodentium-Induced ColitisCell reportsFebruary 5, 2019Wang B, Lim JH, Kajikawa T, Li X, Vallance BA, Moutsopoulos NM, Chavakis T, Hajishengallis G.IL-1β,Leinco Technologies,Cat# I-437 Armenian Hamster IgG isotype control,Leinco Technologies,Cat# I-140 Rat anti-mouse IL-23 p19,ThermoFisher,Cat# 16–7232–81 RRID: AB_842742 Rat IgG1 kappa Isotype Control,ThermoFisher,Cat#

(7) High-Dimensional Analysis Delineates Myeloid and Lymphoid Compartment Remodeling during Successful Immune-Checkpoint Cancer TherapyCellNovember 1, 2018Gubin MM, Esaulova E, Ward JP, Malkova ON, Runci D, Wong P, Noguchi T, Arthur CD, Meng W, Alspach E, et al.HKSP84),Leinco,Cat# I-118 Rat IgG2a (clone 1-1),Leinco,Cat# I-1177 Hamster IgG (clone PIP),Leinco,Cat# I-140 Anti-mouse CD45 (clone 30-F11),Fluidigm,Cat# 3089005B Anti-mouse CD90.2 (clone 30-H12),BioLegend,Cat#

(8) Interferon Regulatory Factor 1 Protects against Chikungunya Virus-Induced Immunopathology by Restricting Infection in Muscle CellsJournal of virologyNovember 15, 2017Nair S, Poddar S, Shimak RM, Diamond MS.blocking monoclonal antibody (MAb H22; Leinco, I-438) or an IgG isotype control antibody (MAb PIP; Leinco, I-140). Foot swelling and virological titers were analyzed at day 2 and/or day 3 after infection. Bone marrow

(9) Plasmodium falciparum histidine-rich protein II causes vascular leakage and exacerbates experimental cerebral malaria in micePLOS ONEMay 5, 2017Priya Pal, Amanda E. Balaban, Michael S. Diamond, Photini Sinnis, Robyn S. Klein, Daniel E. Goldberg(Leinco, I-437) and used for in vivo studies along with an Armenian hamster IgG isotype control (Leinco, I-140), at 300 μg/mouse. Dilutions were made in PBS. HRPII purification The coding sequence for the mature

(10) Progression of type 1 diabetes from the prediabetic stage is controlled by interferon-α signalingProceedings of the National Academy of Sciences of the United States of AmericaApril 4, 2017Marro BS, Ware BC, Zak J, de la Torre JC, Rosen H, Oldstone MB.

(11) Temporally Distinct PD-L1 Expression by Tumor and Host Cells Contributes to Immune EscapeCancer immunology researchFebruary 1, 2017Noguchi T, Ward JP, Gubin MM, Arthur CD, Lee SH, Hundal J, Selby MJ, Graziano RF, Mardis ER, Korman AJ, et al.

(12) Selective Blockade of Interferon-α and -β Reveals Their Non-Redundant Functions in a Mouse Model of West Nile Virus InfectionPloS oneJanuary 1, 2015Sheehan KC, Lazear HM, Diamond MS, Schreiber RD.

(13) Fibrinogen-specific antibody induces abdominal aortic aneurysm in mice through complement lectin pathway activationProceedings of the National Academy of SciencesNovember 12, 2013Hui-fang Zhou, Huimin Yan, Paula Bertram, Ying Hu, Luke E. Springer, Robert W. Thompson, John A. Curci, Dennis E. Hourcade, Christine T. N. PhamH4 generated in house by D.E.H. and P.B.) (Fig. S4), Armenian hamster IgG isoptype control (6 μg/mL; I-140; Leinco Technologies) or rabbit anti-mouse ﬁbrinogen (10 μg/mL; ab34269; Abcam) for 1 h at RT followed

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Armenian Hamster IgG Isotype Control - Purified In vivo GOLD™ Functional Grade - 1.0 mg from Leinco Technologies, Inc.

Leinco Technologies, Inc.

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Armenian Hamster IgG Isotype Control - Purified In vivo GOLD™ Functional Grade - 1.0 mg from Leinco Technologies, Inc.

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